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A microtubule interactome: complexes with roles in cell cycle and mitosis.

Abstract:

The microtubule (MT) cytoskeleton is required for many aspects of cell function, including the transport of intracellular materials, the maintenance of cell polarity, and the regulation of mitosis. These functions are coordinated by MT-associated proteins (MAPs), which work in concert with each other, binding MTs and altering their properties. We have used a MT cosedimentation assay, combined with 1D and 2D PAGE and mass spectrometry, to identify over 250 MAPs from early Drosophila embryos. W...

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Journal:
PLoS biology More from this journal
Volume:
6
Issue:
4
Publication date:
2008-04-22
DOI:
EISSN:
1545-7885
Pubs id:
pubs:97653
UUID:
uuid:cb95a359-bb41-47c3-bec4-a1f041ef1f77
Local pid:
pubs:97653
Source identifiers:
97653
Deposit date:
2012-12-19

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