Journal article
Collagen-induced arthritis in mice: a major role for tumor necrosis factor-alpha.
- Abstract:
-
Collagen-induced arthritis is the most widely used animal model for the evaluation of novel therapeutic strategies for rheumatoid arthritis. The disease is induced by immunization of genetically susceptible strains of mice or rats with type II collagen in adjuvant. Susceptibility to collagen-induced arthritis is associated with major histocompatibility complex (MHC) class II genes, although non-MHC genes also play a role. Both B- and T-lymphocytes are important in the pathogenesis of collagen...
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- Publisher copy:
- 10.1385/1-59745-208-4:265
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Bibliographic Details
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Volume:
- 361
- Pages:
- 265-284
- Publication date:
- 2007-01-01
- DOI:
- EISSN:
-
1940-6029
- ISSN:
-
1064-3745
- URN:
-
uuid:cb91f62f-da18-44ba-8626-6bea7feb2920
- Source identifiers:
-
226810
- Local pid:
- pubs:226810
Item Description
Terms of use
- Copyright date:
- 2007
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