Journal article icon

Journal article

Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alpha.

Abstract:

Granulocyte-macrophage colony-stimulating factor (GM-CSF), in addition to being a growth factor for granulocytes and macrophages, is an activator of cells of the monocyte/macrophage lineage and induces HLA class II expression and cytokine synthesis in these target cells. Macrophage activation and class II expression are prominent features in rheumatoid arthritis (RA) joints, but the mechanism of their stimulation is not understood, since interferon-gamma, the major stimulus of class II expres...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/eji.1830211039

Authors


Haworth, C More by this author
Brennan, FM More by this author
Chantry, D More by this author
Expand authors...
Journal:
European journal of immunology
Volume:
21
Issue:
10
Pages:
2575-2579
Publication date:
1991-10-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:cb8d0697-2a20-4c52-bf2b-02f1d1c36a69
Source identifiers:
481730
Local pid:
pubs:481730

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP