Journal article
Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection.
- Abstract:
-
Understanding the regulation of immune responses is central for control of autoimmune and infectious disease. In murine models of autoimmunity and chronic inflammatory disease, potent regulatory T lymphocytes have recently been characterized. Despite an explosion of interest in these cells, their relevance to human disease has been uncertain. In a longitudinal study of malaria sporozoite infection via the natural route, we provide evidence that regulatory T cells have modifying effects on blo...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.immuni.2005.08.006
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Bibliographic Details
- Journal:
- Immunity
- Volume:
- 23
- Issue:
- 3
- Pages:
- 287-296
- Publication date:
- 2005-09-05
- DOI:
- EISSN:
-
1097-4180
- ISSN:
-
1074-7613
- URN:
-
uuid:cb80bfcd-e1ac-4464-9275-2265656e41e3
- Source identifiers:
-
33233
- Local pid:
- pubs:33233
Item Description
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- Copyright date:
- 2005
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