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Journal article

Non-Arrhenius kinetics for the loop closure of a DNA hairpin.

Abstract:

Intramolecular chain diffusion is an elementary process in the conformational fluctuations of the DNA hairpin-loop. We have studied the temperature and viscosity dependence of a model DNA hairpin-loop by FRET (fluorescence resonance energy transfer) fluctuation spectroscopy (FRETfs). Apparent thermodynamic parameters were obtained by analyzing the correlation amplitude through a two-state model and are consistent with steady-state fluorescence measurements. The kinetics of closing the loop sh...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.101523498

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Physical and Theoretical Chem
Role:
Author
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
98
Issue:
10
Pages:
5584-5589
Publication date:
2001-05-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:cb67410d-56d6-47a9-b8b7-cca2820672e3
Source identifiers:
59808
Local pid:
pubs:59808

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