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Primaquine: the risks and the benefits.

Abstract:

Primaquine is the only generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the only potent gametocytocide in falciparum malaria. Primaquine becomes increasingly important as malaria-endemic countries move towards elimination, and although it is widely recommended, it is commonly not given to malaria patients because of haemolytic toxicity in subjects who are glucose-6-phosphate dehydrogenase (G6PD) deficient (gene frequency typically 3-30% in malaria endemi...

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Publication status:
Published

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Publisher copy:
10.1186/1475-2875-13-418

Authors


Ashley, EA More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Publisher:
BioMed Central Ltd.
Journal:
Malaria journal
Volume:
13
Issue:
1
Pages:
418
Publication date:
2014
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
URN:
uuid:cb5207fb-b1d9-444a-894e-aca21ea7351f
Source identifiers:
489535
Local pid:
pubs:489535
Language:
English
Keywords:

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