Journal article
Normal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1.
- Abstract:
-
The hyaluronan receptor LYVE-1 is expressed abundantly on the surfaces of lymphatic vessels and lymph node sinus endothelial cells from early development, where it has been suggested to function both in cell adhesion/transmigration and as a scavenger for hyaluronan turnover. To investigate the physiological role(s) of LYVE-1, we generated mice in which the gene for the receptor was inactivated by replacement with a beta-galactosidase reporter. LYVE-1(-/-) mice displayed an apparently normal p...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Molecular and cellular biology
- Volume:
- 27
- Issue:
- 2
- Pages:
- 595-604
- Publication date:
- 2007-01-01
- DOI:
- EISSN:
-
1098-5549
- ISSN:
-
0270-7306
- Source identifiers:
-
102709
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:102709
- UUID:
-
uuid:cb3db345-98a1-4cb9-b5a5-34dfdd388683
- Local pid:
- pubs:102709
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2007
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