- Abstract:
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Nicotinic acid adenine dinucleotide phosphate (NAADP) is a potent intracellular second messenger capable of inducing calcium release from acidic organelles and is responsible for many important physiological activities. It has been recognized that an intermediate protein is required for NAADP to mediate its calcium-mobilizing effect through two-pore channels (TPCs). However, the identity of the intermediate NAADP binding protein remains unknown. This thesis aims to identify the elusive NAA...
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- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
- English
- Copyright date:
- 2018
Thesis
Characterization of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Binding Proteins
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