HIV-1 DNA predicts disease progression and post-treatment virological control.
In HIV-1 infection, a population of latently infected cells facilitates viral persistence despite antiretroviral therapy (ART). With the aim of identifying individuals in whom ART might induce a period of viraemic control on stopping therapy, we hypothesised that quantification of the pool of latently infected cells in primary HIV-1 infection (PHI) would predict clinical progression and viral replication following ART. We measured HIV-1 DNA in a highly characterised randomised population of i...Expand abstract
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- Peer review status:
- Peer Reviewed
- Publishers copy is available on ORA
- Copyright holder:
- Williams et al
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- Copyright 2014 Williams et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.
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