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Palladium-catalyzed cascade cyclization of ynamides to azabicycles.

Abstract:
Cascade reactions: A modular assembly of azabicycles by using a cascade cyclization/Suzuki coupling/6π-electrocyclization of bromoenynamides is reported. The reaction offers a wide substituent scope on the bicyclic aminodiene products, which can be selectively oxidized as a general approach to aromatic azabicycles.
Publication status:
Published

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Publisher copy:
10.1002/chem.201102880

Authors


Greenaway, RL More by this author
Campbell, CD More by this author
Holton, OT More by this author
Russell, CA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Journal:
Chemistry (Weinheim an der Bergstrasse, Germany)
Volume:
17
Issue:
51
Pages:
14366-14370
Publication date:
2011-12-05
DOI:
EISSN:
1521-3765
ISSN:
0947-6539
URN:
uuid:cb150ff8-845f-4701-83e5-705697058081
Source identifiers:
206044
Local pid:
pubs:206044

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