- Abstract:
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Small RNAs are functional molecules that modulate mRNA transcripts and have been implicated in the aetiology of several common diseases. However, little is known about the extent of their variability within the human population. Here, we characterise the extent, causes, and effects of naturally occurring variation in expression and sequence of small RNAs from adipose tissue in relation to genotype, gene expression, and metabolic traits in the MuTHER reference cohort. We profiled the expressio...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 960.4kb)
-
- Publisher copy:
- 10.1371/journal.pgen.1002704
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS genetics Journal website
- Volume:
- 8
- Issue:
- 5
- Pages:
- e1002704
- Publication date:
- 2012
- DOI:
- EISSN:
-
1553-7404
- ISSN:
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1553-7390
- URN:
-
uuid:cb0eda14-2813-4aa4-ad11-c97f5429446d
- Source identifiers:
-
332785
- Local pid:
- pubs:332785
- Language:
- English
- Keywords:
- Copyright holder:
- Parts et al.
- Copyright date:
- 2012
- Notes:
- Copyright 2012 Parts et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Extent, causes, and consequences of small RNA expression variation in human adipose tissue.
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