- Abstract:
-
Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system unsurpassed for its variability in disease outcome. It has been observed that axonal loss in MS is significant and that irreversible clinical disability relates to such axonal loss. The clinical similarities between Hereditary Spastic Paraplegia (HSP) and progressive MS, along with their analogous profiles of axonal loss in the long tracts, make the genes known to cause HSP biologically relevant candidates ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/s00415-006-0505-4
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- Journal:
- Journal of neurology
- Volume:
- 254
- Issue:
- 9
- Pages:
- 1221-1226
- Publication date:
- 2007-09-05
- DOI:
- EISSN:
-
1432-1459
- ISSN:
-
0340-5354
- URN:
-
uuid:cb0e51d9-f852-4b08-9172-ba50c21a8ab0
- Source identifiers:
-
33810
- Local pid:
- pubs:33810
- Copyright date:
- 2007
Journal article
The role of hereditary spastic paraplegia related genes in multiple sclerosis. A study of disease susceptibility and clinical outcome.
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