Journal article icon

Journal article

External validation of the bilirubin-atazanavir nomogram for assessment of atazanavir plasma exposure in HIV-1-infected patients.

Abstract:

Atazanavir increases plasma bilirubin levels in a concentration-dependent manner. Due to less costly and readily available assays, bilirubin has been proposed as a marker of atazanavir exposure. In this work, a previously developed nomogram for detection of suboptimal atazanavir exposure is validated against external patient populations. The bilirubin nomogram was validated against 311 matching bilirubin and atazanavir samples from 166 HIV-1-infected Norwegian, French, and Italian patients on...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1208/s12248-012-9440-8

Authors


Expand authors...
Journal:
The AAPS journal
Volume:
15
Issue:
2
Pages:
308-315
Publication date:
2013-04-05
DOI:
EISSN:
1550-7416
ISSN:
1550-7416
URN:
uuid:cb0159ec-7c2e-46af-8b17-e9f87d52867a
Source identifiers:
445525
Local pid:
pubs:445525

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP