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Digital technology in somatic and gene therapy trials of pediatric patients with ocular diseases: protocol for a scoping review

Abstract:
Background: Pharmacogenomics suggests that diseases with similar symptomatic presentations often have varying genetic causes, affecting an individual patient’s response to a specific therapeutic strategy. Gene therapies and somatic cell therapies offer unique therapeutic pathways for ocular diseases and often depend on increased understanding of the genotype-phenotype relationship in disease presentation and progression. While demand for personalized medicine is increasing a... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.2196/10705

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
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Name:
Oxford Academic Health Sciences Centre
More from this funder
Name:
Sir David Cooksey Fellowship in Healthcare Translation
Publisher:
JMIR Publications
Journal:
Journal of Medical Internet Research More from this journal
Volume:
8
Issue:
2
Article number:
e10705
Publication date:
2019-02-07
Acceptance date:
2018-08-26
DOI:
EISSN:
1438-8871
ISSN:
1439-4456
Keywords:
Pubs id:
pubs:834420
UUID:
uuid:caf21698-8cf3-4afd-9116-dc382c458bd8
Local pid:
pubs:834420
Source identifiers:
834420
Deposit date:
2018-04-10

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