Journal article icon

Journal article

Histamine, neuroinflammation and neurodevelopment: a review

Abstract:

The biogenic amine, histamine, has been shown to critically modulate inflammatory processes as well as the properties of neurons and synapses in the brain, and is also implicated in the emergence of neurodevelopmental disorders. Indeed, a reduction in the synthesis of this neuromodulator has been associated with the disorders Tourette’s syndrome and obsessive-compulsive disorder, with evidence that this may be through the disruption of the corticostriatal circuitry during development. Further...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Sub department:
Pharmacology
Role:
Author
ORCID:
0000-0001-9787-3307
More from this funder
Name:
Oxford Hospitals Charity
Grant:
Ref1363
More from this funder
Name:
Medical Research Council
Grant:
MR/M009599/1
Publisher:
Frontiers Media SA
Journal:
Frontiers in Neuroscience More from this journal
Volume:
15
Article number:
680214
Publication date:
2021-07-14
Acceptance date:
2021-06-18
DOI:
EISSN:
1662-453X
Language:
English
Keywords:
Pubs id:
1186719
Local pid:
pubs:1186719
Deposit date:
2021-07-17

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP