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Histamine, neuroinflammation and neurodevelopment: a review

Abstract:

The biogenic amine, histamine, has been shown to critically modulate inflammatory processes as well as the properties of neurons and synapses in the brain, and is also implicated in the emergence of neurodevelopmental disorders. Indeed, a reduction in the synthesis of this neuromodulator has been associated with the disorders Tourette’s syndrome and obsessive-compulsive disorder, with evidence that this may be through the disruption of the corticostriatal circuitry during development. Further...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fnins.2021.680214

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Institution:
University of Oxford
Division:
MSD
Sub department:
Pharmacology
Role:
Author
ORCID:
0000-0001-9787-3307
Publisher:
Frontiers Media SA Publisher's website
Journal:
Frontiers in Neuroscience Journal website
Volume:
15
Article number:
680214
Publication date:
2021-07-14
Acceptance date:
2021-06-18
DOI:
EISSN:
1662-453X
Language:
English
Keywords:
Pubs id:
1186719
Local pid:
pubs:1186719
Deposit date:
2021-07-17

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