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Journal article

Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus.

Abstract:

Horizontal gene transfer is an important driver of bacterial evolution, but genetic exchange in the core genome of clonal species, including the major pathogen Staphylococcus aureus, is incompletely understood. Here we reveal widespread homologous recombination in S. aureus at the species level, in contrast to its near-complete absence between closely related strains. We discover a patchwork of hotspots and coldspots at fine scales falling against a backdrop of broad-scale trends in rate vari...

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Publication status:
Published

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Publisher copy:
10.1038/ncomms4956

Authors


Publisher:
Nature Publishing Group
Journal:
Nature communications More from this journal
Volume:
5
Pages:
3956
Publication date:
2014-01-01
DOI:
EISSN:
2041-1723
ISSN:
2041-1723
Language:
English
Pubs id:
pubs:465923
UUID:
uuid:cad3598b-5fb9-4e0d-a44c-610f56b3502b
Local pid:
pubs:465923
Source identifiers:
465923
Deposit date:
2014-06-12

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