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Journal article

Analysis of the human alpha-globin gene cluster reveals a highly informative genetic locus.

Abstract:

Extensive molecular studies have characterized 15 dimorphic and 2 multiallelic genetic markers within the human alpha-globin gene cluster. Analysis of these markers in 9 populations has shown that the alpha-globin locus is remarkably polymorphic and is therefore an ideal marker on chromosome 16 for the construction of a human genetic linkage map. The combined analysis of 9 polymorphic markers has established alpha-globin haplotypes that provide the means to study the molecular genetics and co...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.83.14.5165

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
83
Issue:
14
Pages:
5165-5169
Publication date:
1986-07-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Source identifiers:
42544
Language:
English
Keywords:
Pubs id:
pubs:42544
UUID:
uuid:caccc292-61e8-4cd2-81ce-7761be02832f
Local pid:
pubs:42544
Deposit date:
2012-12-19

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