- Abstract:
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Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass index, waist circumference, hip circumference, and waist-to-hip-ratio (133,723 individuals) and took forward 348 SNPs into follow-up (additional 137,052 individuals) in a total of 94 studies. Seven loci displayed significant sex-difference (FDR<5%), including four previousl...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 2.9MB)
-
- Publisher copy:
- 10.1371/journal.pgen.1003500
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Volume:
- 9
- Issue:
- 6
- Pages:
- e1003500
- Publication date:
- 2013-06-06
- Acceptance date:
- 2013-03-15
- DOI:
- EISSN:
-
1553-7404
- ISSN:
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1553-7390
- URN:
-
uuid:cac3653e-4da3-4dbd-b346-1d12965b26b5
- Source identifiers:
-
401800
- Local pid:
- pubs:401800
- Language:
- English
- Keywords:
- Copyright holder:
- Randall et al.
- Copyright date:
- 2013
- Notes:
- © 2013 Randall et al. This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.
Journal article
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
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