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Development of a combined cardiac and aortic transplant model to investigate the development of transplant arteriosclerosis in the mouse.

Abstract:

BACKGROUND: The degree of transplant arteriosclerosis in murine cardiac allografts is difficult to assess. Aortic allografts represent an alternative model for evaluating the impact of novel transplant strategies on transplant arteriosclerosis in which the vascular changes can be quantified easily. However, it remains controversial as to whether vascular lesions seen in this model are equivalent to those that develop in solid-organ transplants. The aim of this study was to develop a model of ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation More from this journal
Volume:
19
Issue:
11
Pages:
1039-1046
Publication date:
2000-11-01
DOI:
EISSN:
1557-3117
ISSN:
1053-2498
Language:
English
Keywords:
Pubs id:
pubs:135922
UUID:
uuid:cac3103c-8fbe-4910-9ad7-cc988baac9dc
Local pid:
pubs:135922
Source identifiers:
135922
Deposit date:
2012-12-19

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