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Journal article

Lopinavir–ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Abstract:

Background: Lopinavir–ritonavir has been proposed as a treatment for COVID-19 on the basis of in vitro activity, preclinical studies, and observational studies. Here, we report the results of a randomised trial to assess whether lopinavir–ritonavir improves outcomes in patients admitted to hospital with COVID-19.

Methods: In this randomised, controlled, open-label, platform trial, a range of possible treatments was compared with usual care in patie...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1016/S0140-6736(20)32013-4

Authors


Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Contributor
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Contributor
Publisher:
Elsevier
Journal:
The Lancet More from this journal
Volume:
396
Issue:
10259
Pages:
1345-1352
Publication date:
2020-10-24
Acceptance date:
2020-09-17
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Language:
English
Keywords:
Pubs id:
1133422
Local pid:
pubs:1133422
Deposit date:
2020-09-24

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