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Association of phosphorylation of the T3 antigen with immune activation of T lymphocytes.

Abstract:

In human T lymphocytes the antigen receptor (Ti) is associated non-covalently on the cell surface with the invariant T3 antigen which comprises 3 chains: two glycosylated polypeptides of relative molecular mass 26,000 (Mr 26K) and 21K (gamma and delta) and one non-N-glycosylated polypeptide of Mr 19K (epsilon). The proposed function of T3 is to transduce the activation signals delivered via the antigen receptor. Recently we have shown that phorbol esters, which stimulate protein kinase C, can...

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Publisher copy:
10.1038/325540a0
Journal:
Nature More from this journal
Volume:
325
Issue:
6104
Pages:
540-542
Publication date:
1987-01-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Language:
English
Keywords:
Pubs id:
pubs:482249
UUID:
uuid:cabc8f27-6709-46dd-819c-fc0734ef3787
Local pid:
pubs:482249
Source identifiers:
482249
Deposit date:
2014-09-09

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