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STEREOSPECIFIC AMINO-ACID SYNTHESIS - PREPARATION OF THE GAMMA-ANION DERIVED FROM GLUTAMIC-ACID

Abstract:
Reaction of α-t-butyl γ-methyl N-trityl-L-glutamate (7) with lithium isopropylcyclohexylamide in hexane leads to the specific formation of the γ-ester enolate, a potential synthetic equivalent to the γ-anion synthon for stereospecific α-amino acid synthesis.
Publication status:
Published

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Publisher copy:
10.1039/c39880000828
Journal:
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS
Issue:
12
Pages:
828-829
Publication date:
1988-06-15
DOI:
ISSN:
0022-4936
Language:
English
Pubs id:
pubs:42879
UUID:
uuid:cab476de-41ba-4c53-87ec-32f8b38f0b66
Local pid:
pubs:42879
Source identifiers:
42879
Deposit date:
2012-12-19

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