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Prolonged function of extracorporeal hDAF transgenic pig livers perfused with human blood.

Abstract:

BACKGROUND: The development of genetically modified pigs has renewed interest in the use of porcine liver perfusion in the treatment of acute liver failure. METHOD: A previously developed model of extracorporeal perfusion has been used to test the function of porcine livers transgenic for human decay accelerating factor when perfused with fresh, whole, human blood. Three experimental groups were studied: alloperfusions (normal pig livers perfused with pig blood) and xenoperfusions of both un...

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Journal:
Transplantation More from this journal
Volume:
73
Issue:
8
Pages:
1194-1202
Publication date:
2002-04-01
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
Language:
English
Keywords:
Pubs id:
pubs:147462
UUID:
uuid:cab3a0c8-c5cf-4780-bde5-98e7c3a32a2d
Local pid:
pubs:147462
Source identifiers:
147462
Deposit date:
2012-12-19

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