Journal article
Multi-loop model of Alzheimer disease: an integrated perspective on the Wnt/GSK3β, α-Synuclein, and type 3 diabetes hypotheses
- Abstract:
-
As the prevalence of Alzheimer disease (AD) continues to rise unabated, new models have been put forth to improve our understanding of this devastating condition. Although individual models may have their merits, integrated models may prove more valuable. Indeed, the reliable failures of monotherapies for AD, and the ensuing surrender of major drug companies, suggests that an integrated perspective may be necessary if we are to invent multifaceted treatments that could ultimately prove more s...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Aging Neuroscience Journal website
- Volume:
- 11
- Issue:
- JUL
- Article number:
- 184
- Publication date:
- 2019-07-31
- Acceptance date:
- 2019-07-05
- DOI:
- EISSN:
-
1663-4365
- ISSN:
-
1663-4365
- Pmid:
-
31417394
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1046711
- Local pid:
- pubs:1046711
- Deposit date:
- 2020-06-15
Terms of use
- Copyright holder:
- Norwitz et al.
- Copyright date:
- 2019
- Rights statement:
- © 2019 Norwitz, Mota, Norwitz and Clarke. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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