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A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos.

Abstract:
Between June and October 2000 we conducted the first randomized trial in Laos comparing chloroquine (CQ) with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated Plasmodium falciparum malaria (n = 29, 42-d follow-up, age > 5 years). The proportion of patients with treatment failure was high (CQ = 78%, RIII 46%; SP = 36%, RIII 15%). The treatment policy for uncomplicated P. falciparum malaria in Laos needs to be reviewed urgently.
Publication status:
Published

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Authors


Phetsouvanh, R More by this author
Phompida, S More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Khanthavong, M More by this author
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Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume:
97
Issue:
3
Pages:
343-344
Publication date:
2003
DOI:
EISSN:
1878-3503
ISSN:
0035-9203
URN:
uuid:caa6ea13-4f11-4c67-9a72-9899f72d35d4
Source identifiers:
738
Local pid:
pubs:738

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