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Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study.

Abstract:

OBJECTIVES: Osteolysis and subsequent prosthesis loosening is the most common cause for revision following total knee arthroplasty (TKA) or total hip arthroplasty (THA). Hormone replacement therapy (HRT) could reduce osteolysis through its antiresorptive effects. We studied whether HRT use is associated with reduced revision rates in a community-based cohort of women undergoing TKA or THA for osteoarthritis. METHODS: Female participants in the General Practice Research Database undergoing a p...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Publisher:
BMJ Publishing Group
Journal:
Annals of the Rheumatic Diseases More from this journal
Volume:
74
Issue:
3
Pages:
557-563
Publication date:
2014-01-01
DOI:
EISSN:
1468-2060
ISSN:
0003-4967
Language:
English
Keywords:
UUID:
uuid:caa48ef9-b221-40df-b963-d6eec3521d79
Local pid:
pubs:446833
Source identifiers:
446833
Deposit date:
2014-01-30

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