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Journal article

Harnessing the properties of dendritic cells in the pursuit of immunological tolerance

Abstract:

The acquisition of self-perpetuating, immunological tolerance specific for graft alloantigens has long been described as the “holy grail” of clinical transplantation. By removing the need for life-long immunosuppression following engraftment, the adverse consequences of immunosuppressive regimens, including chronic infections and malignancy, may be avoided. Furthermore, autoimmune diseases and allergy are, by definition, driven by aberrant immunological responses to ordinarily innocuous antig...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bj.2017.01.002

Authors


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Institution:
University of Oxford
Division:
UAS
Department:
Academic Administration Division
Sub department:
Divisional Administration
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Oxford college:
Trinity College
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Biomedical Journal Journal website
Volume:
40
Issue:
2
Pages:
80–93
Publication date:
2017-04-01
Acceptance date:
2017-01-16
DOI:
EISSN:
2320-2890
ISSN:
2319-4170
Source identifiers:
694270
Keywords:
Pubs id:
pubs:694270
UUID:
uuid:ca8fea17-bfb7-4039-92d9-d8dbfca0d8e8
Local pid:
pubs:694270
Deposit date:
2017-05-13

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