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Thesis

Genome-wide association of statin-induced myopathy

Abstract:

Lowering LDL-cholesterol with statin therapy produces substantial reductions in cardiovascular events, and larger cholesterol reductions may produce larger benefits. Rarely, myopathy occurs with statins, especially at higher doses and in combination with certain medications. Similarly strong associations might exist between myopathy with high-dose statin regimens and genetic variants, especially those affecting blood statin levels. This study aimed to find genetic variants associated with ...

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Institution:
University of Oxford
Research group:
Heart Studies Group
Oxford college:
Green College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Clinical Trial Service Unit

Contributors

Role:
Supervisor
Role:
Supervisor
Publication date:
2009
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:ca675486-d678-4200-8bb4-988a923e9c4c
Local pid:
ora:11446

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