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Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle

Abstract:

The Mycobacterium tuberculosis complex (MTBC) is the collective term given to the group of bacteria that cause tuberculosis (TB) in mammals. It has been reported that M. tuberculosis H37Rv, a standard reference MTBC strain, is attenuated in cattle compared to Mycobacterium bovis. However, as M. tuberculosis H37Rv was isolated in the early 1930s, and genetic variants are known to exist, we sought to revisit this question of attenuation of M. tuberculosis for cattle by performing a bovine exper...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1038/s41598-017-18575-5

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Role:
Author
ORCID:
0000-0001-7655-3144
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Funding agency for:
Rue-Albrecht, K
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Grant:
Seventh Framework Programme: FP7-228394
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Grant:
Investigator Award 08/IN.1/B2038
Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
8
Issue:
1
Pages:
1-13
Chapter number:
894
Publication date:
2018-01-17
Acceptance date:
2017-12-13
DOI:
EISSN:
2045-2322
Pubs id:
pubs:822110
URN:
uri:ca64a10c-5b7e-447c-a0e9-19b42763b054
UUID:
uuid:ca64a10c-5b7e-447c-a0e9-19b42763b054
Local pid:
pubs:822110

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