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New templates for HIV-1 antibody-based vaccine design

Abstract:
A current strategy for the design of neutralizing antibody-based vaccines to prevent HIV-1 transmission is that of reverse engineering, starting from a neutralizing antibody and working back to reconstruct its epitope by structure-based design technology. However, the field has been impeded by a lack of appropriate antibodies for use as templates. Recently, new antibodies have been described that may fulfil this role, invigorating the field. © 2010 Faculty of 1000 Ltd.

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Publisher copy:
10.3410/B2-60

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
F1000 Biology Reports More from this journal
Volume:
2
Issue:
1
Publication date:
2010-01-01
DOI:
EISSN:
1757-594X
ISSN:
1740-4118
Language:
English
Pubs id:
pubs:103799
UUID:
uuid:ca5d8bb1-b060-4471-8201-4a9d8f8cc658
Local pid:
pubs:103799
Source identifiers:
103799
Deposit date:
2013-02-20

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