Journal article
Tumour-stromal interactions in acid-mediated invasion: a mathematical model.
- Abstract:
-
It is well established that the tumour microenvironment can both promote and suppress tumour growth and invasion, however, most mathematical models of invasion view the normal tissue as inhibiting tumour progression via immune modulation or spatial constraint. In particular, the production of acid by tumour cells and the subsequent creation of a low extracellular pH environment has been explored in several 'acid-mediated tumour invasion' models where the acidic environment facilitates normal ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.jtbi.2010.08.028
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Bibliographic Details
- Journal:
- Journal of theoretical biology
- Volume:
- 267
- Issue:
- 3
- Pages:
- 461-470
- Publication date:
- 2010-12-01
- DOI:
- EISSN:
-
1095-8541
- ISSN:
-
0022-5193
- Source identifiers:
-
71159
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:71159
- UUID:
-
uuid:ca54c7b2-0ba9-4163-97c9-98328174784f
- Local pid:
- pubs:71159
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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