- Abstract:
-
At present, neither a selective antiviral therapy nor a vaccine is available for HCV, and the current treatment is only effective in a fraction of patients. Given the recent demonstration that antiviral compounds targeting the NS5B polymerase and the NS3/4A protease lead to rapid selection for resistance, iminosugar derivatives as HCV assembly inhibitors were characterized for drug resistance. It has been previously shown that deoxynojirimycin (DNJ)-containing iminosugars are potent HCV antiv...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1016/S0168-8278(10)60673-3
-
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of Hepatology Journal website
- Volume:
- 52
- Pages:
- S261-S262
- Publication date:
- 2010
- DOI:
- ISSN:
-
0168-8278
- URN:
-
uuid:ca51c17f-8eb1-473e-bd27-7bf46cd1b6c7
- Source identifiers:
-
100734
- Local pid:
- pubs:100734
- Copyright date:
- 2010
Journal article
No evidence for drug resistance by iminosugar-based HCV assembly inhibitors in tissue culture
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