Journal article
No evidence for drug resistance by iminosugar-based HCV assembly inhibitors in tissue culture
- Abstract:
-
At present, neither a selective antiviral therapy nor a vaccine is available for HCV, and the current treatment is only effective in a fraction of patients. Given the recent demonstration that antiviral compounds targeting the NS5B polymerase and the NS3/4A protease lead to rapid selection for resistance, iminosugar derivatives as HCV assembly inhibitors were characterized for drug resistance. It has been previously shown that deoxynojirimycin (DNJ)-containing iminosugars are potent HCV antiv...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/S0168-8278(10)60673-3
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of Hepatology Journal website
- Volume:
- 52
- Pages:
- S261-S262
- Publication date:
- 2010-04-13
- DOI:
- ISSN:
-
0168-8278
- Source identifiers:
-
100734
Item Description
- Pubs id:
-
pubs:100734
- UUID:
-
uuid:ca51c17f-8eb1-473e-bd27-7bf46cd1b6c7
- Local pid:
- pubs:100734
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- European Association for the Study of the Liver
- Copyright date:
- 2010
- Notes:
- © 2010 European Association for the Study of the Liver. Published by Elsevier Ireland Ltd. All rights reserved.
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