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Per-arnt-sim (PAS) domain kinase (PASK) as a regulator of glucagon secretion.

Abstract:

The physiological and pathophysiological regulation of glucagon secretion from pancreatic alpha cells remains a hotly debated topic. The mechanism(s) contributing to the glucose sensitivity of glucagon release and its impaired regulation in diabetes remain unclear. A paper in the current issue of Diabetologia by da Silva Xavier and colleagues (doi: 10.1007/s00125-010-2010-7 ) provides intriguing new insight into a metabolic sensing pathway mediated by the per-arnt-sim (PAS) domain kinase (PAS...

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Publication status:
Published

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Publisher copy:
10.1007/s00125-011-2072-1
Journal:
Diabetologia More from this journal
Volume:
54
Issue:
4
Pages:
719-721
Publication date:
2011-04-01
DOI:
EISSN:
1432-0428
ISSN:
0012-186X
Language:
English
Keywords:
Pubs id:
pubs:118078
UUID:
uuid:ca397e6e-eae0-4e28-9f84-5dd4bcc26e0b
Local pid:
pubs:118078
Source identifiers:
118078
Deposit date:
2012-12-19

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