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Linkage analysis of candidate genes as susceptibility loci for osteoarthritis-suggestive linkage of COL9A1 to female hip osteoarthritis.

Abstract:

OBJECTIVE: To examine 11 candidate genes as susceptibility loci for osteoarthritis (OA). METHODS: A total of 481 families have been ascertained in which at least two siblings have had joint replacement surgery of the hip, or knee, or hip and knee for idiopathic OA. Each candidate gene was targeted using one or more intragenic or closely linked microsatellite marker. The linkage data were analysed unstratified and following stratification by sex and by joint replaced (hip or knee). RESULTS: T...

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Publication status:
Published

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Authors


Mustafa, Z More by this author
Chapman, K More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Clipsham, K More by this author
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Journal:
Rheumatology (Oxford, England)
Volume:
39
Issue:
3
Pages:
299-306
Publication date:
2000-03-05
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
URN:
uuid:ca3862b2-2729-41de-b068-f03bf570d957
Source identifiers:
103819
Local pid:
pubs:103819

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