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Characterization of adhesive interactions between human endothelial cells and megakaryocytes

Abstract:

Cell-cell adhesion is essential for many immunological functions and is believed to be important in the regulation of hematopoiesis. Adhesive interactions between human endothelial cells and megakaryocytes were characterized in vitro using the CMK megakaryocytic cell line as well as marrow megakaryocytes. Although there was no adhesion between unactivated human umbilical vein endothelial cells (HUVEC) and megakaryocytes, treatment of HUVEC with inflammatory cytokines such as IL-1 beta, tumor ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1172/jci116470

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Publisher:
American Society for Clinical Investigation Publisher's website
Journal:
Journal of Clinical Investigation Journal website
Volume:
91
Issue:
6
Pages:
2378-2384
Publication date:
1993-06-01
DOI:
EISSN:
1558-8238
ISSN:
0021-9738
Source identifiers:
223747
Language:
English
Keywords:
Pubs id:
pubs:223747
UUID:
uuid:ca333906-1e7f-4ceb-89b0-5815731601dc
Local pid:
pubs:223747
Deposit date:
2012-12-19

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