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Telomere length and physical performance at older ages: an individual participant meta-analysis

Abstract:

Telomeres are involved in cellular ageing and shorten with increasing age. If telomere length is a valuable biomarker of ageing, then telomere shortening should be associated with worse physical performance, an ageing trait, but evidence for such an association is lacking. The purpose of this study was to examine whether change in telomere length is associated with physical performance.Using data from four UK adult cohorts (ages 53-80 years at baseline), we undertook cross-sectional and longi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author
Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
8
Issue:
7
Pages:
e69526
Publication date:
2013-07-26
Acceptance date:
2013-06-12
DOI:
EISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:417365
UUID:
uuid:ca20d3de-a9e2-4747-8d5a-2d4ce6848c12
Local pid:
pubs:417365
Source identifiers:
417365
Deposit date:
2013-11-17

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