Journal article
Modulation of osteogenic differentiation in human skeletal cells in Vitro by 5-azacytidine.
- Abstract:
-
Cellular differentiation is controlled by a variety of factors including gene methylation, which represses particular genes as cell fate is determined. The incorporation of 5-azacytidine (5azaC) into DNA in vitro prevents methylation and thus can alter cellular differentiation pathways. Human bone marrow fibroblasts and MG63 cells treated with 5azaC were used as models of osteogenic progenitors and of a more mature osteoblast phenotype, respectively. The capacity for differentiation of these ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1006/cbir.1998.0240
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Authors
Bibliographic Details
- Journal:
- Cell biology international
- Volume:
- 22
- Issue:
- 3
- Pages:
- 207-215
- Publication date:
- 1998-01-01
- DOI:
- EISSN:
-
1095-8355
- ISSN:
-
1065-6995
- Source identifiers:
-
108416
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:108416
- UUID:
-
uuid:ca1d6812-0af9-4218-a17c-9a9c2751bb4e
- Local pid:
- pubs:108416
- Deposit date:
- 2014-02-16
Terms of use
- Copyright date:
- 1998
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