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New findings regarding the epidemic history and population dynamics of Japan-indigenous genotype 3 hepatitis E virus inferred by molecular evolution.

Abstract:

BACKGROUND: Since previous studies have investigated the population dynamics of Japan-indigenous genotype 3 hepatitis E virus (HEV) using virus sequences, more nucleotide sequences have been determined, and new techniques have been developed for such analysis. AIMS: To prevent future hepatitis E epidemic in Japan, this study aimed to elucidate the cause of past HEV expansion. METHODS: The epidemic history of Japan-indigenous genotype 3 HEV was determined using the coalescent analysis framewo...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
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Journal:
Liver international : official journal of the International Association for the Study of the Liver
Volume:
32
Issue:
4
Pages:
675-688
Publication date:
2012-04-01
DOI:
EISSN:
1478-3231
ISSN:
1478-3223
Source identifiers:
221747

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