Journal article icon

Journal article

A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose.

Abstract:

PURPOSE: Current methods for quantifying effects of DNA repair modifiers on radiation sensitivity assume a constant effect independent of the radiation dose received. The aim of this study was to develop and evaluate a modelling strategy by which radiation dose dependent effects of DNA repair inhibitors on clonogenic survival might be identified and their significance assessed. METHODS: An indicator model that allowed quantification of the Sensitiser Effect on Radiation response as a function...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1186/1742-4682-4-25

Authors


Journal:
Theoretical biology and medical modelling
Volume:
4
Issue:
1
Pages:
25
Publication date:
2007-01-01
DOI:
EISSN:
1742-4682
ISSN:
1742-4682
URN:
uuid:ca04de75-36ff-4e58-8686-b192ee336d67
Source identifiers:
288217
Local pid:
pubs:288217

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP