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Magnetic resonance imaging of the time course of hyperpolarized 129Xe gas exchange in the human lungs and heart

Abstract:
Purpose To perform magnetic resonance imaging (MRI), human lung imaging, and quantification of the gas-transfer dynamics of hyperpolarized xenon-129 (HPX) from the alveoli into the blood plasma. Materials and methods HPX MRI with iterative decomposition of water and fat with echo asymmetry and least-square estimation (IDEAL) approach were used with multi-interleaved spiral k-space sampling to obtain HPX gas and dissolved phase images. IDEAL time-series image... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1007/s00330-018-5853-9

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
ORCID:
0000-0002-5945-2090
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
RDM Cardiovascular Medicine
Phillips, J-A More by this author
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Publisher:
Springer Berlin Heidelberg Publisher's website
Journal:
European Radiology Journal website
Volume:
29
Issue:
5
Pages:
2283–2292
Publication date:
2018-12-05
Acceptance date:
2018-10-23
DOI:
EISSN:
1432-1084
ISSN:
0938-7994
Pubs id:
pubs:951371
URN:
uri:c9eca9ec-2a78-433f-9632-c1dbe8553c63
UUID:
uuid:c9eca9ec-2a78-433f-9632-c1dbe8553c63
Local pid:
pubs:951371

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