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Comparison of O-polysaccharide and hemolysin co-regulated protein as target antigens for serodiagnosis of melioidosis.

Abstract:

Background

Melioidosis is a severe disease caused by Burkholderia pseudomallei. Clinical manifestations are diverse and acute infections require immediate treatment with effective antibiotics. While culture is the current diagnostic standard, it is time-consuming and has low sensitivity. In endemic areas, inaccessibility to biosafety level 3 facilities and a lack of good serodiagnostic tools can impede diagnosis and disease surveillance. Recent studies have suggested that O-polys...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pntd.0005499

Authors


Pumpuang, A More by this author
More by this author
Department:
Oxford, MSD, NDM, Tropical Medicine
Phokrai, P More by this author
Jenjaroen, K More by this author
Sintiprungrat, K More by this author
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Contributors

Role:
Editor
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Funding agency for:
Dunachie, SJ
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Funding agency for:
Dunachie, SJ
Newton Fund Institutional Links More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Neglected Tropical Diseases Journal website
Volume:
11
Issue:
3
Pages:
e0005499
Publication date:
2017-03-05
Acceptance date:
2017-03-17
DOI:
ISSN:
1935-2727 and 1935-2735
Pubs id:
pubs:688904
URN:
uri:c9e03bde-34e9-4d17-9f27-8e209c9fee7b
UUID:
uuid:c9e03bde-34e9-4d17-9f27-8e209c9fee7b
Local pid:
pubs:688904

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