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Journal article

Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis.

Abstract:

UNLABELLED: Liver metastasis from colorectal cancer is a leading cause of cancer mortality. Myeloid cells play pivotal roles in the metastatic process, but their prometastatic functions in liver metastasis remain incompletely understood. To investigate their role, we simulated liver metastasis in C57BL/6 mice through intrasplenic inoculation of MC38 colon carcinoma cells. Among the heterogeneous myeloid infiltrate, we identified a distinct population of CD11b/Gr1(mid) cells different from oth...

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Publication status:
Published

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Publisher copy:
10.1002/hep.26094

Authors


Gordon-Weeks, AN More by this author
Tapmeier, TT More by this author
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Journal:
Hepatology (Baltimore, Md.)
Volume:
57
Issue:
2
Pages:
829-839
Publication date:
2013-02-05
DOI:
EISSN:
1527-3350
ISSN:
0270-9139
URN:
uuid:c9d67a95-6a12-4f70-8bf3-bd77bb3895ae
Source identifiers:
355631
Local pid:
pubs:355631

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