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Journal article

Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis.

Abstract:

UNLABELLED: Liver metastasis from colorectal cancer is a leading cause of cancer mortality. Myeloid cells play pivotal roles in the metastatic process, but their prometastatic functions in liver metastasis remain incompletely understood. To investigate their role, we simulated liver metastasis in C57BL/6 mice through intrasplenic inoculation of MC38 colon carcinoma cells. Among the heterogeneous myeloid infiltrate, we identified a distinct population of CD11b/Gr1(mid) cells different from oth...

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Publication status:
Published

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Publisher copy:
10.1002/hep.26094

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Journal:
Hepatology (Baltimore, Md.)
Volume:
57
Issue:
2
Pages:
829-839
Publication date:
2013-02-01
DOI:
EISSN:
1527-3350
ISSN:
0270-9139
Source identifiers:
355631
Language:
English
Keywords:
Pubs id:
pubs:355631
UUID:
uuid:c9d67a95-6a12-4f70-8bf3-bd77bb3895ae
Local pid:
pubs:355631
Deposit date:
2013-11-16

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