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Journal article

The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy.

Abstract:

Abnormal uterine activity in pregnancy causes a range of important clinical disorders, including preterm birth, dysfunctional labour and post-partum haemorrhage. Uterine contractile patterns are controlled by the generation of complex electrical signals at the myometrial smooth muscle plasma membrane. To identify novel targets to treat conditions associated with uterine dysfunction, we undertook a genome-wide screen of potassium channels that are enriched in myometrial smooth muscle. Comput...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


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Name:
March of Dimes
Grant:
21‐FY12‐133
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Name:
National Institute of Health
Grant:
R01 HD‐037831
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Name:
Action Medical Research
Grant:
SP4507
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Name:
Medical Research Council
Grant:
G0901801
Publisher:
EMBO Press
Publication date:
2014-01-01
DOI:
EISSN:
1757-4684
ISSN:
1757-4676
Language:
eng
Keywords:
Pubs id:
pubs:477605
UUID:
uuid:c9d3c34a-af4d-4dcc-b976-e39e2f13224d
Local pid:
pubs:477605
Source identifiers:
477605
Deposit date:
2016-02-09

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