The HIV-1-containing macrophage compartment: a perfect cellular niche?

Journal article

Macrophages are a major target of HIV-1 infection and are believed to act as viral reservoirs and mediators of HIV-1-associated neurological damage. These pathological roles may be associated with the ability of the virus to assemble and accumulate in apparently intracellular compartments in macrophages. These so-called virus-containing compartments were initially thought to be late endosomes or multivesicular bodies, but it has since been shown that they are distinct structures that have com...

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Authors: Tan, J; Sattentau, Q

• Publication status: Published
• Journal: Trends in microbiology
• Volume: 21
• Issue: 8
• Pages: 405-412
• Publication date: 2013-08-01
• DOI: 10.1016/j.tim.2013.05.001
• EISSN: 1878-4380
• ISSN: 0966-842X
• Language: English
• Keywords: Humans; Organelles; Macrophages; HIV-1