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The HIV-1-containing macrophage compartment: a perfect cellular niche?

Abstract:

Macrophages are a major target of HIV-1 infection and are believed to act as viral reservoirs and mediators of HIV-1-associated neurological damage. These pathological roles may be associated with the ability of the virus to assemble and accumulate in apparently intracellular compartments in macrophages. These so-called virus-containing compartments were initially thought to be late endosomes or multivesicular bodies, but it has since been shown that they are distinct structures that have com...

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Publication status:
Published

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Publisher copy:
10.1016/j.tim.2013.05.001

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Trends in microbiology More from this journal
Volume:
21
Issue:
8
Pages:
405-412
Publication date:
2013-08-01
DOI:
EISSN:
1878-4380
ISSN:
0966-842X
Language:
English
Keywords:
Pubs id:
pubs:407461
UUID:
uuid:c9d3bd8b-1e10-4b60-b66d-7a665e3eaa42
Local pid:
pubs:407461
Source identifiers:
407461
Deposit date:
2013-11-16

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