Molecular overlap of the IgA target antigens in the subepidermal blistering diseases.

Journal article

Linear IgA disease (LAD) has circulating IgA auto-antibodies which have been found to be associated with epidermal- and dermal-derived antigens. The localization and molecular weight(s) of the IgA target antigen(s) implicated in LAD and their relationship to the target antigens for the IgA antibodies in bullous pemphigoid (BP) and cicatricial pemphigoid (CP) are unknown. Sera from patients with all 3 diseases who had circulating IgA antibodies were studied by immunoblotting with both epiderma...

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Authors: Collier, P; Wojnarowska, F; Allen, J; Kirtschig, G

• Publication status: Published
• Journal: Dermatology (Basel, Switzerland)
• Volume: 189 Suppl 1
• Issue: SUPPL. 1
• Pages: 105-107
• Publication date: 1994-01-01
• DOI: 10.1159/000246945
• EISSN: 1421-9832
• ISSN: 1018-8665
• Language: English
• Keywords: Humans; Pemphigoid, Bullous; Skin Diseases, Vesiculobullous; Immunoblotting; Autoantigens; Molecular Weight; Basement Membrane; Skin; Pemphigoid, Benign Mucous Membrane; Autoantibodies; Immunoglobulin A