- Abstract:
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BACKGROUND: Bacterial infection of the pleural space often causes adherence of the pleural membranes by fibrous tissue, probably mediated by inflammation initiated by bacterial cell-wall motifs, including lipoteichoic acid-T (LTA-T). We postulated that therapeutically administered LTA-T might produce a similar effect, achieving control of malignant pleural effusion (pleurodesis). METHODS: Patients with histocytologically proven symptomatic malignant pleural effusions were included in this pha...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s1470-2045(08)70205-5
-
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- Journal:
- The Lancet. Oncology
- Volume:
- 9
- Issue:
- 10
- Pages:
- 946-952
- Publication date:
- 2008-10-05
- DOI:
- EISSN:
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1474-5488
- ISSN:
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1470-2045
- URN:
-
uuid:c9c4f6a1-b79e-41a7-a1cb-6b6388edd02c
- Source identifiers:
-
14201
- Local pid:
- pubs:14201
- Copyright date:
- 2008
Journal article
Use of lipoteichoic acid-T for pleurodesis in malignant pleural effusion: a phase I toxicity and dose-escalation study.
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