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Journal article

Antibiotic treatment and flares of rheumatoid arthritis: a self-controlled case series study analysis using CPRD GOLD

Abstract:

There is emerging evidence of the impact of infections on rheumatoid arthritis pathogenesis and flares. We aimed to study the association between antibiotic use (and timing of use), and the occurrence of flares in patients with RA. We nested a self-controlled case series (SCCS) of patients who have RA flares within a newly diagnosed RA cohort (n = 31,992) from the UK Clinical Practice Research Datalink (CPRD) GOLD dataset. We determined associations between exposure to antibiotics (beta-lacta...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41598-019-45435-1

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
Publisher:
Springer Nature
Journal:
Scientific Reports More from this journal
Volume:
9
Article number:
8941
Publication date:
2019-06-20
Acceptance date:
2019-06-06
DOI:
EISSN:
2045-2322
Pubs id:
pubs:1011013
UUID:
uuid:c9c1dc18-ad63-471e-85f5-61c1823323f9
Local pid:
pubs:1011013
Source identifiers:
1011013
Deposit date:
2019-06-11

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