- Abstract:
-
Objective
To investigate the prospective associations between adiposity and lipid-related variables and conversion to MS, time to subsequent relapse and progression in disability.
Methods
A cohort of 279 participants with a first clinical diagnosis of CNS demyelination was prospectively followed to 5-year review. Height, weight, waist and hip circumference were measured, and serum samples taken for measurement of lipids and apolipoproteins. Survival analysis was u...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 367.9KB)
-
- Publisher copy:
- 10.1136/jnnp-2016-315037
-
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- Publisher:
- BMJ Publishing Group Publisher's website
- Journal:
- Journal of Neurology, Neurosurgery, and Psychiatry Journal website
- Volume:
- 88
- Issue:
- 5
- Pages:
- 395-401
- Publication date:
- 2017-03-20
- Acceptance date:
- 2017-02-21
- DOI:
- EISSN:
-
1468-330X
- ISSN:
-
0022-3050
- Pubs id:
-
pubs:687281
- URN:
-
uri:c9c1389b-595d-462e-998a-676ce083f412
- UUID:
-
uuid:c9c1389b-595d-462e-998a-676ce083f412
- Local pid:
- pubs:687281
- Copyright holder:
- Dwyer et al
- Copyright date:
- 2017
- Notes:
- © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is the accepted manuscript version of the article. The final version is available online from the BMJ Publishing Group at: http://dx.doi.org/10.1136/jnnp-2016-315037
Journal article
An adverse lipid profile and increased levels of adiposity significantly predict clinical course after a first demyelinating event
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Funding
National Health and Medical Research Council
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National Health and Medical Research Council of Australia
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