- Abstract:
-
Macrophage Scavenger Receptor A (SR-A) is a major non-opsonic receptor for Neisseria meningitidis on mononuclear phagocytes in vitro, and the surface proteins NMB0278, NMB0667, and NMB1220 have been identified as ligands for SR-A. In this study we ascertain the in vivo role of SR-A in the recognition of N. meningitidis MC58 (serogroup B) in a murine model of meningococcal septicaemia. We infected wild-type and SR-A(-/-) animals intraperitoneally with N. meningitidis MC58 and monitored their h...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 361.5kb)
-
- Publisher copy:
- 10.1371/journal.ppat.1000297
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS pathogens Journal website
- Volume:
- 5
- Issue:
- 2
- Pages:
- e1000297
- Publication date:
- 2009-02-05
- DOI:
- EISSN:
-
1553-7374
- ISSN:
-
1553-7366
- URN:
-
uuid:c9bdb3b6-44b7-4c72-b79b-079a84f9e206
- Source identifiers:
-
5918
- Local pid:
- pubs:5918
- Language:
- English
- Keywords:
- Copyright holder:
- Plüddemann et al.
- Copyright date:
- 2009
- Notes:
- © 2009 Plüddemann et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
The macrophage scavenger receptor A is host-protective in experimental meningococcal septicaemia.
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