Journal article
The macrophage scavenger receptor A is host-protective in experimental meningococcal septicaemia.
- Abstract:
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Macrophage Scavenger Receptor A (SR-A) is a major non-opsonic receptor for Neisseria meningitidis on mononuclear phagocytes in vitro, and the surface proteins NMB0278, NMB0667, and NMB1220 have been identified as ligands for SR-A. In this study we ascertain the in vivo role of SR-A in the recognition of N. meningitidis MC58 (serogroup B) in a murine model of meningococcal septicaemia. We infected wild-type and SR-A(-/-) animals intraperitoneally with N. meningitidis MC58 and monitored their h...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 361.5KB)
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- Publisher copy:
- 10.1371/journal.ppat.1000297
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Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS pathogens Journal website
- Volume:
- 5
- Issue:
- 2
- Pages:
- e1000297
- Publication date:
- 2009-02-01
- DOI:
- EISSN:
-
1553-7374
- ISSN:
-
1553-7366
- Source identifiers:
-
5918
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:c9bdb3b6-44b7-4c72-b79b-079a84f9e206
- Local pid:
- pubs:5918
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Plüddemann et al
- Copyright date:
- 2009
- Notes:
- © 2009 Plüddemann et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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