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Journal article

Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease.

Abstract:

BACKGROUND and AIMS: Toll-like receptors (TLR) are innate immune receptors involved in recognition of the intestinal microflora; they are expressed by numerous cell types in the intestine, including epithelial cells, myeloid cells, and lymphocytes. Little is known about the relative contributions of TLR signaling in distinct cellular compartments to intestinal homeostasis. We aimed to define the roles of TLR signals in distinct cell types in the induction and regulation of chronic intestinal...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Gastroenterology
Volume:
139
Issue:
2
Pages:
519-529.e2
Publication date:
2010-08-05
DOI:
EISSN:
1528-0012
ISSN:
0016-5085
URN:
uuid:c9b47e37-48e8-468b-8ee9-ff948aec54a3
Source identifiers:
54669
Local pid:
pubs:54669

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